Amoclav 1gm


Product Description


Amoxicillin and Clavulanic Acid

Tablet, Powder for Suspension and Injections


Amoclav® is an antibacterial combination consisting of the antibiotic Amoxicillin

and the β-lactamase inhibitor Clavulanic Acid.

Indication and Usage

Amoclav® is indicated for short-term treatment of bacterial infections at the

following sites:

  1. URTI (including ENT); e.g., tonsillitis, sinusitis, otitis media.
  2. LRTI; e.g., acute and chronic bronchitis, lobar and bronchopneumonia.
  3. Genito-urinary tract infections; e.g., cystitis, urethritis, pyelonephritis.
  4. SSTI.
  5. Bone and joint infections; e.g., osteomyelitis.
  6. Other infections; e.g., septic abortion, puerperal sepsis, intra-abdominal

sepsis, etc.

Dosage and Administrations

Dose of Tablets

Adults and children over 12 years:

The usual adult dose is one Amoclav® 625 Tablet every 12 hours or one Amoclav®375 Tablet every 8 hours.

Dose of Powder for Suspensions

Amoclav® Powder for Suspension:

1–6 years: 5 ml 3 times daily or 0.25 ml/kg 3 times daily

6–12 years: 10 ml 3 times dailyAmoclav® bid Powder for Suspension:

Dose of Injections:


Usually 1.2 g every 8 hours, increased in more severe infections to 1.2 g

every 6 hours.


Amoclav® should be used with care in patients on anti-coagulation therapy or

with severe hepatic dysfunction.


History of Penicillin hypersensitivity.

Side Effects

Urticarial and erythematous rashes sometimes occur.

In common with other beta-lactam antibiotics angioedema and anaphylaxis have been reported.

Use in Pregnancy and Lactation

Amoclav® in pregnancy is not recommended unless considered essential by the physician. During lactation, trace quantities of Amoxicillin can be detected in breast milk.

Drug Interaction

Prolongation of bleeding time and prothrombin time has been reported in

some patients receiving Amoclav®.

Amoclav® 1 g Tablet: Each box contains 6 tablets in 1X6’s Alu-Alu form packs.

Each film coated tablet contains Amoxicillin 875 mg and Clavulanic Acid125 mg.



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