LOXIM 200 MG
Loxim200 mg Tab: Each tablet contains Cefixime trihydrate BP equivalent to Cefixime 200 mg.
Description: Loxim (Cefixime) is a third generation cephalosporin antibiotic for oral administration. Cefixime is a bactericidal.
Mode of action: Cefixime binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death.
Indications: Treatment of uncomplicated UTIs, otitis media, pharyngitis, tonsillitis, acute bronchitis,
acute exacerbations of chronic bronchitis, and uncomplicated gonorrhea caused by susceptible strain
of specific organisms.
Reconstitution: Loxim 50 ml PDF: First shake the bottle to loosen the powder. Then add 30 ml boiled
and cool water into the bottle with the supplied cup and shake well to make 50 ml suspension.
Dosage & administration: Adult: 200-400 mg/day as a single dose or in 2 divided doses. Child: 8
mg/kg/day as a single dose or in 2 divided doses; <6 months: Not recommended. Treatment should be
continued for 48 hr after disappearance of symptoms.
Side-effects: Cefixime is generally well-tolerated. Diarrhea; Gas; Loose stools; Nausea; Stomach pain or
Precaution: Prescribing Cefixime for Oral Suspension in the absence of a proven or strongly suspected
bacterial infection of a prophylactic indication may rise the risk of development of drug-resistant
bacteria. Particularly during prolonged treatment, careful observation of the patient is essential
Pregnancy Category & lactation: Pregnancy category: B (US).
Lactation: No history found about the secretion of cefixime in the human milk.
Contraindication: Contraindicated in patients with known allergy to the Cephalosporin group of
Drug interaction: Vitamins, minerals, herbal products etc may cause interaction with Loxim (Cefixime).
Overdose: Gastric lavage may be indicated; otherwise, no specific antidote exists. Cefixime is not removed in significant quantities from the circulation by hemodialysis or peritoneal dialysis.
Storage: Store at room temperature & protect from light. Keep
200mg: 2X6’s Tablet;